Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

1. Auflage 2011
ISBN: 978-1-119-97291-4
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 314 Seiten, E-Book

Many small molecules occur naturally as "messenger" chemicals whichregulate the behaviour and functions of microbes, plants, insectsand animals. Examples include hormones, pheromones, phytoalexins,and antifeedants. These biofunctional molecules are of greatinterest to researchers in helping develop our understanding ofbiological function and in the development of new drugs. Howeverextracting them from nature can be prohibitively expensive, sothere is great interest in devising methods of synthesising themfrom simple starting materials in the laboratory.

Chemical Synthesis of Hormones, Pheromones and OtherBioregulators is an introduction to the techniques andstrategies for the synthesis of biofunctional small molecules.Topics include:

* what are biofunctional molecules?

* why must biofunctional molecules be synthesized?

* how can we synthesize biofunctional molecules?

* the synthesis of phytohormones, phytoalexins and otherbiofunctional molecules of plant origin

* the synthesis of insect juvenile hormones and antifeedants

* the synthesis of pheromones and the significance of chiralityin pheromone science

* the synthesis of microbial hormones and pheromones,antibiotics, and other biofunctional molecules of microbialorigin

* the synthesis of marine antifeedants and medicinalcandidates

* a synthetic examination of incorrectly proposed structures ofbiomolecules

* reflections on science as a human endeavor

Drawing on a career of almost 50 years researching and teachingthis subject, Kenji Mori's Chemical Synthesis of Hormones,Pheromones and Other Bioregulators is a must-have textbook forstudents and researchers of organic synthesis and natural products,and a stimulating and inspiring account of a distinguished chemicalcareer.

Autoren/Hrsg.

Mori, Kenji

Über Autor(innen)

Professor Kenji Mori has nearly 50 years experience researching and teaching the synthesis of biofunctional small molecules. He has been awarded the Japan Academy Prize (1981), the Silver Medal of the International Society of Chemical Ecology (1996), the American Chemical Society's Ernest Guenther Award in the Chemistry of Natural Products (1999), the Special Prize of the Society of Synthetic Organic Chemistry, Japan (2003), and the Frantisek Sorm Memorial Medal of the Academy of Sciences of the Czech Republic (2003). He is the author of "The Total Synthesis of Natural Products, Vol. 9" (Wiley, 1992), considered by many to be the authoritative volume on pheromone synthesis, and over 750 peer-reviewed research papers.