Ohlsson / Hall / Ritzen | Genomic Imprinting | Buch | 978-0-521-47243-2 | sack.de

Buch, Englisch, 392 Seiten, Format (B × H): 179 mm x 255 mm, Gewicht: 955 g

Ohlsson / Hall / Ritzen

Genomic Imprinting

Causes and Consequences
Erscheinungsjahr 1995
ISBN: 978-0-521-47243-2
Verlag: Cambridge University Press

Causes and Consequences

Buch, Englisch, 392 Seiten, Format (B × H): 179 mm x 255 mm, Gewicht: 955 g

ISBN: 978-0-521-47243-2
Verlag: Cambridge University Press


Originally published in 1995, this significant publication on genomic or parental imprinting was prepared by an outstanding team of international authorities. Genomic imprinting results in the preferential expression of one allele, depending on the parent of origin. It is associated with several disease syndromes in humans. Interest in this area has expanded rapidly from the time when it was first recognised that some aspects of inheritance were not adequately explained by the Mendelian laws. The chapters cover a wealth of material to help explain not only the mechanisms of genomic imprinting but also its biological and medical consequences. This interdisciplinary volume encompasses clinical genetics, pathology, developmental biology, evolution and genetics. It will be of interest to all scientists and clinicians working in this area.
Ohlsson / Hall / Ritzen Genomic Imprinting jetzt bestellen!

Weitere Infos & Material


Contributors; Part I. Genomic Imprinting in Mammals: 1. The role of imprinting in early mammalian development A. Gilligan, and D. Solter; 2. The evolution of parental imprinting: a review of hypotheses D. Haig and R. Trivers; 3. Genetic variations in parental imprinting on mouse chromosome 17 J. Forejt, S. Gregorovà, M. Landíková, J. Capková and L. M. Silver; Part II. Chromatin Structure and DNA Modifications: 4. Epigenetic inheritance: the chromatin connection A. P. Wolffe; 5. Chromobox genes and the molecular mechanisms of cellular determination P. B. Singh and T. C. James; 6. The biochemical basis of allele-specific gene expression in genomic imprinting and X inactivation T. H. Bestor; 7. DNA methylation and mammalian development R. Jaenisch, C. Beard and E. Li; Part III. Mechanisms of Imprinting: 8. X chromosome inactivation and imprinting M. F. Lyon; 9. Imprinting of H19 and Xist in uniparental embryos M. A. Surani, A. C. Ferguson-Smith, H. Sasaki and S. C. Barton; 10. Imprinted genes, allelic methylation, and imprinted modifiers of methylation W. Reik, R. Feil, N. D. Allen, T. F. Moore and J. Walter; 11. Genomic imprinting of the H19 and Igf2 genes in the mouse S. M. Tilgham, M. S. Bartolomei, A. L. Webber, M. E. Brunkow, J. Saam, P. A. Leighton and K. Pfeifer; 12. Plasticity of imprinting R. Ohlsson, T. Ekström, G. Franklin, S. Pfeifer-Ohlsson, H. Cui, S. Miller, R. Fisher and C. Walsh; 13. Regional regulation of allele-specific gene expression I. Simon and H. Cedar; Part IV. Genomic Imprinting in Embryonal Tumors and Overgrowth Disorders: 14. Genomic imprinting in embryonal tumors and overgrowth disorders A. E. Reeve; 15. Tracking imprinting: the Beckwith-Wiedemann syndrome M. Mannens; 16. Genomic imprinting in Beckwith-Wiedemann syndrome R. Weksberg and J. Squire; 17. Mitotic crossing over and the disruption of genomic imprinting G. B. Côté; 18. Evaluating H19 as an imprinted tumor suppressor gene B. Tycko; 19. A domain of abnormal imprinting in human cancer A. P. Feinberg; Part V. Genomic Imprinting and the Prader-Willi Syndrome: 20. Parent-of-origin-specific DNA methylation and imprinting mutations on human chromosome 15 B. Horsthemke, B. Dittrich and K. Buiting; 21. The SNRPN gene and Prader-Willi syndrome U. Francke, J. A. Kerns and J. Giacalone; Part VI. Imprinting: A Search for New Genes and Unifying Principles: 22. Use of chromosome rearrangements for investigations into imprinting in the mouse B. M. Cattanach, J. Barr and J. Jones; 23. A new imprinted gene, U2af-related sequence, isolated by a methylation-sensitive genome scanning method T. Mukai, I. Hatada, T. Yamaoka, K. Kitagawa, X.-D. Wang, T. Sugama, J. Masuda and J. Ogata; 24. The mouse Igf2/MPR gene: a model for all gametic imprinted genes? D. P. Barlow; Index.


Ihre Fragen, Wünsche oder Anmerkungen
Vorname*
Nachname*
Ihre E-Mail-Adresse*
Kundennr.
Ihre Nachricht*
Lediglich mit * gekennzeichnete Felder sind Pflichtfelder.
Wenn Sie die im Kontaktformular eingegebenen Daten durch Klick auf den nachfolgenden Button übersenden, erklären Sie sich damit einverstanden, dass wir Ihr Angaben für die Beantwortung Ihrer Anfrage verwenden. Selbstverständlich werden Ihre Daten vertraulich behandelt und nicht an Dritte weitergegeben. Sie können der Verwendung Ihrer Daten jederzeit widersprechen. Das Datenhandling bei Sack Fachmedien erklären wir Ihnen in unserer Datenschutzerklärung.