Protein-Nucleic Acids Interactions

Erscheinungsjahr 2013
ISBN: 978-0-12-411637-5
Verlag: William Andrew Publishing

Buch, Englisch, 216 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 390 g

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Zielgruppe

Biochemists, biophysicists, cell biologists, protein chemists, structural geneticists, and structural biologists

Autoren/Hrsg.

Weitere Mitwirkende

Donev, Rossen

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Proteinforschung

Inhaltsverzeichnis

- Proliferating Cell Nuclear Antigen (PCNA) Structure and Interactions. Too Many Partners for One Dancer?

Alfredo De Biasio and Francisco J. Blanco

- Anomalous Protein-DNA Interactions Behind Neurological Disorders

Sergio Camero, María J Benítez and Juan S. Jiménez

- Computational Approaches for Predicting the Binding Sites and Understanding the Recognition Mechanism of Protein-DNA Complexes

M. Michael Gromiha and R. Nagarajan

- Detecting DNA-Protein Interactions in Living Cells - ChIP Approach

Rossitza Christova

- DNA Sequence Motif: A Jack of all Trades for ChIP-Seq Data Ivan V. Kulakovskiy and Vsevolod J. Makeev

Über Autor(innen)

Donev, Rossen
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.