Buch, Englisch, 572 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 960 g
Buch, Englisch, 572 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 960 g
ISBN: 978-0-12-182786-1
Verlag: William Andrew Publishing
Zielgruppe
Biochemists, cell biologists, molecular biologists, geneticists and biophysicists
Fachgebiete
Weitere Infos & Material
Section I: Mitochondrial Ubiquinone and Reductases
1: Mitochondrial Quinone Reductases: Complex I
2: Q-Cycle Bypass Reactions at the Qo Site of the Cytochrome bc1 (and Related) Complexes
3: Targeting Coenzyme Q Derivatives to Mitochondria
4: The Mitochondrial Interplay of Ubiquinol and Nitric Oxide in Endotoxemia
5: Mitochondrial Respiratory Chain Dysfunction Caused by Coenzyme Q Deficiency
6: Coenzyme Q Cytoprotective Mechanisms
7: Dietary Coenzyme Q10 and Mitochondrial Status
Section II: Anticancer Quinones and Quinone Oxidoreductases
8: NAD(P)H:Quinone Oxidoreductase 1 (NQO1, DT-Diaphorase), Functions and Pharmacogenetics
9: Structure and Mechanism of NAD[P]H:Quinone Acceptor Oxidoreductases (NQO)
10: Diaziridinylbenzoquinones
11: Quinone Reductase-Mediated Nitro-Reduction: Clinical Applications
12: Bioactivation and Resistance to Mitomycin C
13: NAD(P)H:Quinone Oxidoreductase 1 Expression, Hydrogen Peroxide Levels, and Growth Phase in HeLa Cells
14: The "Prochaska� Microtiter Plate Bioassay for Inducers of NQO1
15: Structure-Activity Relationships in Two-Electron Reduction of Quinones
16: p53-Dependent Apoptosis and NAD(P)H:Quinone Oxidoreductase 1
17: The Role of Endogenous Catechol Quinones in the Initiation of Cancer and Neurodegenerative Diseases
18: Induction of NQO1 in Cancer Cells
Section III: Quinone Reductases: Chemoprevention and Nutrition
19: Role of Nicotinamide Quinone Oxidoreductase 1 (NQO1) in Protection against Toxicity of Electrophiles and Reactive Oxygen Intermediates
20: Activation and Detoxification of Naphthoquinones by NAD(P)H: Quinone Oxidoreductase
21: Induction of Quinone Reductase as a Primary Screen for Natural Product Anticarcinogens
22: Chemoprevention by 1,2-Dithiole-3-Thiones Through Induction of NQO1 and Other Phase 2 Enzymes
23: Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1)
24: Induction of Phase II Enzymes by Aliphatic Sulfides Derived from Garlic and Onions: An Overview
25: Upregulation of Quinone Reductase by Glucosinolate Hydrolysis Products From Dietary Broccoli
Section IV: Quinones and Age-Related Diseases
26: Therapeutic Effects of Coenzyme Q10 in Neurodegenerative Diseases
27: Neuroprotective Actions of Coenzyme Q10 in Parkinson's Disease
Author Index
Subject Index