Schlücker Surface Enhanced Raman Spectroscopy

Analytical, Biophysical and Life Science Applications
1. Auflage 2013
ISBN: 978-3-527-63276-3
Verlag: Wiley-VCH
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 332 Seiten, E-Book

Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical

and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems.

 

From the contents:

 

* Theory and practice of SERS

* Analytical applications

* SERS combined with other analytical techniques

* Biophysical applications

* Life science applications including various microscopies

 

Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.

Autoren/Hrsg.

Schlücker, Sebastian

Weitere Mitwirkende

Kiefer, Wolfgang

Inhaltsverzeichnis

Preface

 

BASIC ELECTROMAGNETIC THEORY OF SERS

Introduction

Plasmon Resonances and Field Enhancements

Field Enhancement Distribution and Localization

Electromagnetic Model for the SERS and Fluorescence Enhancement Factors

The Magnitude of the SERS Enhancement Factor in Typical Cases

Conclusions

 

NANOPARTICLE SERS SUBSTRATES

Introduction

Preparation and Stability of Metal Nanoparticle Colloidal SERS Substrates

Characterization of Nanoparticle-Based SERS Substrates

Nanoparticles on the Unfunctionalized Solid Surface as SERS Substrates

Conclusion and Outlook

 

QUANTITATIVE SERS METHODS

Introduction

SERS Media

Stability and Shelf Life

Reproducibility and Internal Standards

Selectivity

Conclusion

 

SINGLE-MOLECULE- AND TRACE DETECTION BY SERS

Introduction

Experiments and Results

Conclusions

 

DETECTION OF PERSISTENT ORGANIC POLLUTANTS BY USING SERS SENSORS BASED ON ORGANICALLY FUNCTIONALIZED Ag NANOPARTICLES

Introduction

Inclusion Hosts

Contact Hosts

Occlusion Hosts

Conclusions

 

SERS AND PHARMACEUTICALS

Introduction

SERS of Antipyretics and Analgesics

SERS of Antimalarials

SERS of Anticarcinogenics andf Antimutagenics

Concluding Remarks

 

SERS AND SEPARATION SCIENCE

Introduction

SERS and Capillary Electrophoresis (CE)

SERS and Liquid Chromatography (LC)

SERS and Gas Chromatography (GC)

SERS and Thin Layer Chromatography (TLC)

Other Separation Methods

Conclusions

 

SERS AND MICROFLUIDICS

Introduction

Lab-on-a-Chip Technology

Microfluidic Platforms and Application for SERS

Summary

 

ELECTROCHEMICAL SERS AND ITS APPLICATION IN ANALYTICAL, BIOPHYSICAL AND LIFE SCIENCE

Electrochemical Surface-Enhanced Raman Spectroscopy

Features of Electrochemical Surface-Enhanced Raman Spectroscopy

Experimental Techniques of EC-SERS

Applications of EC-SERS

Perspectives

 

ELECTRON TRANSFER OF PROTEINS AT MEMBRANE MODELS

Introduction

Model Membranes and Membrane Models

Methods for Probing Electron Transfer Processes of Cytochrome c at Coated Electrodes

The Unusual Distance Dependence of the Interfacial Electron Transfer Process

Electron Transfer and Protein Orientational Dynamics

Electric Field Effects on the Electron Transfer Dynamics

Electron Transfer and Protein Structural Changes

Overall Description of the Mechanism and Dynamics of the Interfacial Processes

Interfacial Electric Fields and the Biological Functions of Cytochrome c

 

QUANTITATIVE DNA ANALYSIS USING SURFACE-ENHANCED RESONANCE RAMAN SCATTERING

Introduction

SERRS Surfaces

Raman Reporters

SERRS DNA Probes

Sensitivity

Multiplexing

Assays

Conclusion

 

SERS MICROSCOPY: NANOPARTICLE PROBES AND BIOMEDICAL APPLICATIONS

Introduction

SERS Nanoparticle Probes

Biomedical Applications of SERS Microscopy

Summary and Outlook

 

1-P AND 2-P EXCITED SERS AS INTRACELLULAR PROBE

From Tags to Probes: Challenges in Intracellular Probing

Probing of Intracellular Parameters

Surface-Enhanced Hyper Raman Scattering and Its Potential in Studies of Cells

 

SURFACE- AND TIP-ENHANCEMENT CARS

Introduction

CARS: Coherent Anti-Stokes Raman Scattering

Local Enhancement of CARS by Metallic Nanostructures

Surface-Enhanced CARS

Tip-Enhanced CARS

Über Autor(innen)

Sebastian Schlücker obtained his undergraduate and PhD degrees at the University of Würzburg, Germany. After a postdoctoral stay at the US National Institutes of Health (NIH), Bethesda, Maryland, USA from 2002 till 2004, he completed his Habilitation in Physical Chemistry at the University of Würzburg in 2006. He has been Professor of Experimental Physics at the University of Osnabrück, Germany since 2008.