Diagnostic Molecular Biology

Erscheinungsjahr 2019
ISBN: 978-0-12-802823-0
Verlag: William Andrew Publishing

Buch, Englisch, 472 Seiten, Format (B × H): 216 mm x 276 mm, Gewicht: 1290 g

Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding.

The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations. This book also covers the applications of the principles and techniques currently employed in the clinical laboratory.

Zielgruppe

<p>researchers and technicians in the lab, pathologists, and students in molecular biology and microbiology</p>

Autoren/Hrsg.

Shen, Chang-Hui

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Mikrobiologie

Inhaltsverzeichnis

Part I1. Nucleic Acids: DNA and RNA2. Nucleic Acid-Based Cellular Activities3. Gene Expression: Transcription of the Genetic Code4. Gene Expression: Translation of the Genetic Code5. The Genome

Part II6. Extraction and Purification of Nucleic Acids and Proteins7. Detection and Analysis of Nucleic Acids8. Quantification and Analysis of Proteins9. Amplification of Nucleic Acids10. Characterization of Nucleic Acids and Proteins11. Techniques in Sequencing12. Genome and Transcriptome Analysis

Part III13. Molecular Diagnosis of Chromosomal Disorders14. Molecular Diagnosis of Mutation and Inherited Diseases15. Molecular Diagnosis of Infectious Diseases16. Guidance for Molecular Clinical Laboratory

Über Autor(innen)

Shen, Chang-Hui
Chang-Hui Shen, PhD, is a Professor of Biology and Biochemistry at the College of Staten Island and the Graduate Center, City University of New York. He earned his B.S. and M.S. at the National Chung-Hsing University, Taiwan, and his Ph.D. at the University of Edinburgh, UK. He was a visiting fellow of the National Institutes of Health before joining the City University of New York.

Dr. Shen's research focuses on the mechanism of gene expression, with an emphasis on epigenetic regulation in gene activation. His lab utilizes the breadth of current and advanced techniques in molecular biology and biochemistry. He has published dozens of articles throughout his career, and his research has been supported by several agencies, including NATO, NIH, and NSF.