Phytopharmaceuticals and Herbal Drugs

Prospects and Safety Issues in the Delivery of Natural Products
Erscheinungsjahr 2023
ISBN: 978-0-323-99125-4
Verlag: William Andrew Publishing

Buch, Englisch, Format (B × H): 191 mm x 235 mm, Gewicht: 450 g

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource.

This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

Autoren/Hrsg.

Singh, Manju Rawat

Singh, Deependra

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Komplementäre Medizin, Asiatische Medizin (TCM), Heilpraktiker
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

Section I. Prospects of Plant Based Therapeutics 1. Plant based therapeutics: Current status and future perspectives 2. Worldwide health scenario from the perspective of herbal medicine research

Section II. Challenges and Delivery Aspects of Phytomedicines and Bioactives 3. Challenges in delivery of plant actives 4. Lipid based particulate systems for delivery of plant actives and extracts: Extraction, prospective carriers and safety issues 5. Phyto-complexed systems as versatile tool for delivery of plant-based drugs 6. Impact of nanotechnology on herbal bioactives: An overview 7. Application of nanomedicine for efficient delivery of herbal bioactives 8. Nanophytomedicine: Nanotechnology for herbal product development and value addition

Section III. Safety Considerations, Regulatory and Commercial Aspects 9. Safety considerations in designing phytopharmaceuticals 10. Herbal drug interactions and effects on Phytopharmaceuticals 11. Clinical, ethical and regulatory issues of botanicals 12. Commercial aspect and market potential of phytoactive products

Section IV. Application Aspects of Phytopharmaceuticals 13. Interactions between radiopharmaceutical products and herbal medicines 14. Use of microfluidic organ-on-a-chip systems for screening and development of phytopharmaceuticals and herbal drugs 15. New and revisited approaches on the transdermal delivery of polyphenols-loaded nanoparticles for melanoma prevention and treatment 16. Novel drug delivery approaches for improving therapeutic applications of Berberine and Berberin-rich herbal preparations 17. Impact of phytomedicines and their novel delivery systems as an alternative for the treatment of neurodegenerative disorders 18. Role of phytopharmaceuticals in inflammatory disorders

Über Autor(innen)

Singh, Manju Rawat
Dr. Manju Singh obtained her M.Pharm in Pharmaceutical biotechnology from the Department of Pharmaceutical sciences, Dr. H.S. Gour Central University, Sagar in 2004 and Ph.D from University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India in 2009 where she is currently working as assistant professor. She has around 18 years of teaching and research experience. Her prime research area includes designing strategies for protein and peptide delivery, topical systems for autoimmune disorders like psoriasis, rheumatoid arthritis, inflammatory bowel disease and experimental designing using advanced statistical and mathematical modeling methods. She has 80 research and review papers published in national and international journals. She has citations more than 3000 with h-index 28 and i10 index of 49 (Google scholar) and scopus h-index 21; 4100 citations. She has 2 international and 1 Indian patent. She has successfully completed several projects funded by Indian council of medical research (ICMR), university grants commission (UGC), C.G. state council of science and technology (CGCOST), and Department of science and technology (DST). She is recipient of DHR-ICMR international fellowship 2014-15 and number of awards at national and state level for excellence in research viz. Young scientist award of the state of Chhattisgarh 2006 in biotechnology. She has been bestowed with Best Teacher award (Assistant Professor) of Pt. Ravishankar Shukla University in science section 2016. She is a life member of various professional bodies like Indian Pharmaceutical association (IPA), Association of Pharmacy teachers of India (APTI), Indian Pharmacy Graduates Association (IPGA). She had been visiting scientist at School of Pharmacy, Department of Pharmaceutics, University of Mississippi, Oxford, USA 2015. She is engaged in research projects focused on studying the role of plant bioactives in devising new treatments mainly for autoimmune disorders and inflammatory diseases in collaboration with various universities in India and abroad.

Singh, Deependra
Dr. Deependra Singh is presently working as assistant professor at University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India. He is a central member of the Pharmacy council of India. He has around 18 years of teaching and research experience. His prime research area includes formulation of multiple bioactive delivery systems like multiphase hydrogels, nanosystems, microspheres for wound management, advanced statistical and mathematical modelling methods, Tissue Culture Techniques, nutraceuticals and designing novel systems for plant actives and extracts. He has more than 90 research and review papers published in national and international journals. He has successfully completed projects funded by UGC, AICTE, DST and several industrial projects. He has citations more than 4000 with h-index 28 and i10 index of 49 (Google scholar) and scopus h-index 21; 4100 citations. He has 2 international and 1 Indian patent. He is recipient of prestigious Department of health research-ICMR young Indian biomedical scientist award 2019, UGC RAMAN international award 2014 and UGC Research Award 2012 by university Grants Commission, New Delhi. He has prestigious awards at state level for excellence in research viz.; Young scientist award of the state of Chhattisgarh 2006 in medical sciences. He is state evaluator and trainee for national children science congress. He is a life member of various professional bodies like Indian Pharmaceutical association (IPA), Association of Pharmacy teachers of India (APTI), Indian Society of Pharmacognosy (ISP) and serving as President, Chhattisgarh state branch APTI 2013 (Elected); Secretary, Chhattisgarh state branch IPA. He had been visiting scientist at National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Mississippi USA.