Stem Cells in Development and Disease

Erscheinungsjahr 2014
ISBN: 978-0-12-416022-4
Verlag: William Andrew Publishing

Buch, Englisch, 472 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 860 g

This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a comprehensive set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging

Zielgruppe

Researchers in cell, developmental, and molecular biology; genetics

Autoren/Hrsg.

Weitere Mitwirkende

Rendl, Michael

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Embryologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Histologie
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie

Inhaltsverzeichnis

1. Mechanisms of Pluripotency In Vivo and In Vitro
2. Hematopoietic Stem Cell Development: An Epigenetic Journey
3. Intestinal Stem Cells and their Defining Niche
4. Epithelial Stem Cells in Adult Skin
5. The Mammary Stem Cell Hierarchy
6. Satellite Cells: The Architects of Skeletal Muscle
7. Neural Stem Cells of the Hippocampus: Development, Physiology Regulation and Dysfunction in Disease
8. Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease
9. Spermatogonial Stem Cell Functions in Physiological and Pathological Conditions
10. The Origin, Biology, and Therapeutic Potential of Facultative Adult Hepatic Progenitor Cells
11. Nephron Progenitor Cells: Shifting the Balance of Self-Renewal and Differentiation
12. Adult Stem Cell Niches: Cellular and Molecular Components
13. Cancer Stem Cells, Pluripotency, and Cellular Heterogeneity: A WNTer Perspective
14. Cellular Mechanisms of Somatic Stem Cell Aging