Telomeres in Health and Disease

Erscheinungsjahr 2014
ISBN: 978-0-12-397898-1
Verlag: William Andrew Publishing

Buch, Englisch, 202 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field.

Zielgruppe

PhDs in the fields of molecular and cellular biology and MDs and physician-scientists in internal medicine, hematology, oncology, pulmonology, and gastroenterology.

Autoren/Hrsg.

Weitere Mitwirkende

Calado, Rodrigo

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin
• Naturwissenschaften Biowissenschaften Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Innere Medizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Pneumologie, Atmung, Asthma
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

- Telomere and Telomerase Biology
Miriam Aparecida Giardini, Marcela Segatto, Marcelo Santos da Silva, Vinícius Santana Nunes and Maria Isabel Nogueira Cano
- Human Telomeres and Telomere Biology Disorders
Sharon A. Savage
- Telomere Biology in Stem Cells and Reprogramming
Luis F. Z. Batista
- Telomere Dynamics and Aging
Geraldine Aubert
- Telomeres in Molecular Epidemiology Studies
Clara Bodelon, Sharon A. Savage and Shahinaz M. Gadalla
- Telomere dysfunction and hematologic disorders
Raquel M. A. Paiva and Rodrigo T. Calado
- The Role of Telomeres in Liver Disease
Yoshiaki Sunami, Guido von Figura, Alexander Kleger, Pavel Strnad, Norbert Hüser and Daniel Hartmann
- Telomeres in lung diseases
Rodrigo T. Calado

Über Autor(innen)

Calado, Rodrigo
Rodrigo Calado received his MD in 1997 and PhD in 2003 both from the University of São Paulo, Brazil. He was trained in hematology and did his postdoctoral fellowship at the U. S. National Institutes of Health in Bethesda, Maryland with Dr. Neal S. Young, where he also worked as a Staff Scientist between 2007 and 2011. He is currently Associate Professor of Medicine at the University of São Paulo in Ribeirão Preto, Brazil. Dr. Calado was the first to report on telomerase enzyme mutations in humans causing disease (aplastic anemia) and found that telomerase complex mutations also predisposed to leukemia and liver cirrhosis. He also demonstrated that short telomeres increase chromosome instability in humans and that sex hormones up-regulate telomerase function in hematopoietic cells.