Buch, Englisch, 445 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1100 g
Buch, Englisch, 445 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1100 g
ISBN: 978-1-55938-835-1
Verlag: Elsevier Science & Technology
The advances in molecular biology have led to a major insight in establishing precise diagnosis and treatment of many cancers resulting in prevention of death. The field is expanding so rapidly that a complete account of all aspects of genetics of cancer could not be accommodated within the scope of a single volume format. Nevertheless, a few very specific topics have been chosen, which readers may find of great interest in hopes that their interest may be rejuvenated concerning the bewildering nature of this deadly disease. The contributors to Volume 3 have provided up-to-date accounts of their fields of expertise. Although the contributors have kept their chapters brief, they include an extensive bibliography for those who wish to understand a particular topic in depth.
For more than a century, cancer has been diagnosed on the enigmatic basis of morphological features. Establishing a diagnosis based on DNA, RNA, and proteins, which is done routinely now, was once inconceivable. Cloning a gene of hematopoietic origin is no longer a fantasy. The approach has shifted over the past 15 years from identification of chromosomal abnormalities toward zeroing in on cancer genes.
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tiergenetik, Reproduktion
- Naturwissenschaften Biowissenschaften Proteinforschung
- Naturwissenschaften Biowissenschaften Molekularbiologie
- Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
- Naturwissenschaften Biowissenschaften Botanik Pflanzenreproduktion, Verbreitung, Genetik
Weitere Infos & Material
List of Contributors. Preface (R.S. Verma). Genetics of Human Cancer: An Overview (R.S. Verma). Oncogenes in Tumor Progression (B.P. Himelstein and R.J. Muschel). The p53 Tumor Suppressor Gene (T. Soussi). Genetic Aspects of Tumor Suppressor Genes (B.E. Weissman and K. Conway). P21ras: From Oncoprotein to Signal Transducer (J.L. Bos and B.M.T. Burgering). Chromosomal Basis of Hematologic Malignancies (R.S. Verma). The Molecular Genetics of Chromosomal Translocations in Lymphoid Malignancy (F.G. Haluska and G. Russo).