Application of Clinical Bioinformatics

Softcover Nachdruck of the original 1. Auflage 2016
ISBN: 978-94-024-1375-5
Verlag: Springer Netherlands

Buch, Englisch, Band 11, 398 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 6823 g

Reihe: Translational Bioinformatics

This book

elucidates how genetic, biological and medical information can be applied to

the development of personalized healthcare, medication and therapies. Focusing

on aspects of the development of evidence-based approaches in bioinformatics

and computational medicine, including data integration, methodologies, tools

and models for clinical and translational medicine, it offers an essential

introduction to clinical bioinformatics for clinical researchers and

physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong

Wang is a distinguished Professor of Medicine. He is Director of Shanghai

Institute of Clinical Bioinformatics, Director of Fudan University Center for

Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research

Institute, Director of Biomedical Research Center, Fudan University Zhongshan

Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health

Care and Biomedical Engineering at Institute of Health Care Engineering with

European Notified Body of Medical Devices, Graz University of Technology, Graz,

Austria; Dr. Denis Shields is a Professor of Clinical

Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng

is a Professor at Department of Biostatistics and Bioinformatics, Tulane University

School of Public Health and Tropical Medicine, USA; Dr. Jacques S

Beckmann is a Professor and Director of Section of Clinical Bioinformatics,

Swiss Institute of Bioinformatics, Switzerland.

Zielgruppe

Research

Autoren/Hrsg.

Wang, Xiangdong

Baumgartner, Christian

Beckmann, Jacques S

Shields, Denis C.

Deng, Hong-Wen

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizinische Mathematik & Informatik
• Naturwissenschaften Biowissenschaften Angewandte Biologie Bioinformatik

Inhaltsverzeichnis

The Era of Big Data: From Data-driven Research to Data-driven Clinical
Care.- Biostatistics, data mining and computational modeling.- Gene expression
and profiling.- The next generation sequencing and
applications in clinical research.- Clinical epigenetics and epigenomics.- Proteomic
profiling: Data mining and analyses.- Targeted metabolomics: the next
generation of clinical chemistry!?.- Clinical bioinformatics for biomarker
discovery in targeted metabolomics.- Metagenomic Profiling, Interaction of
Genomics with Meta-genomics.- Clinical Epigenetics and Epigenomics.- Integrative
Biological Databases.- Standards and Regulations for (Bio)Medical Software.- Clinical
applications and systems biomedicine.- Key Law and Policy Considerations for
Clinical Bioinformaticians.- Challenges and Opportunities in Clinical
Bioinformatics.- Heterogeneity of Hepatocellular Carcinoma.