Chemical Genomics

Small Molecule Probes to Study Cellular Function
Softcover Nachdruck of the original 1. Auflage 2006
ISBN: 978-3-662-51797-0
Verlag: Springer

Buch, Englisch, Band 58, 179 Seiten, Paperback, Format (B × H): 148 mm x 210 mm, Gewicht: 261 g

Reihe: Ernst Schering Foundation Symposium Proceedings

Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry. The Ernst Schering Research Foundation Workshop 58 was organized to bring together scientific leaders in the field to discuss the implications of chemical genomics for drug discovery. Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.

Zielgruppe

Research

Autoren/Hrsg.

Weinmann, Hilmar

Jaroch, Stefan

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

Chemogenomics in Drug Discovery.- Chemogenomics Strategies for G-Protein Coupled Receptor Hit Finding.- Chemogenomics Approaches to G-Protein Coupled Receptor Lead Finding.- Diversity Oriented Synthesis: A Challenge for Synthetic Chemists.- Probing Protein Function with Small Molecules.- Tamoxifen-Based Probes for the Study of Estrogen Receptor-Mediated Transcription.- Protein Structure Similarity Clustering and Natural Product Structure as Guiding Principles for Chemical Genomics.- Tackling the Chemogenomic Space by Novel Screening Technologies.