York / Kompella / Shekunov Supercritical Fluid Technology for Drug Product Development

1. Auflage 2004
ISBN: 978-0-203-02137-8
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 632 Seiten

Reihe: Drugs and the Pharmaceutical Sciences

Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical products-from drug powders for respiratory delivery to drug delivery systems for controlled release.

Zielgruppe

Pharmaceutical engineers and analysts; engineers and scientists working with SCF technologies; and undergraduate and graduate students in physical pharmaceutics, pharmaceutical technology, chemical engineering, and related disciplines.

Autoren/Hrsg.

York, Peter

Kompella, Uday B.

Shekunov, Boris Y.

Fachgebiete

• Wirtschaftswissenschaften Wirtschaftssektoren & Branchen Fertigungsindustrie Pharmaindustrie

Inhaltsverzeichnis

Chemistry and Materials Design for Pharmaceutical Applications. Phase Equilibrium in Solid-Liquid-Supercritical Fluid Systems. Mechanisms of Particle Formation Using Supercritical Fluids. Methods of Particle Production. Colloid and Interface Science for CO2-based Pharmaceutical Processes. Production of Powders for Respiratory Drug Delivery. Control of Physical Form of Drug Substances. Supercritical Fluid Impregnation of Polymers for Drug Delivery. Formulation of Controlled Drug Release Systems. Processing of Biological Materials. Asymmetric Catalysis in Supercritical Fluids. Analytical and Semi-Preparative Supercritical Fluid Chromatography in Drug Discovery. Drug Extraction Development and Potential of Critical Fluid Technology in the Neutraceutical Industry. Scale-Up Issues for Supercritical Fluid Processing in Compliance with GMP