Intracellular Delivery II

Fundamentals and Applications
2014
ISBN: 978-94-017-8895-3
Verlag: Springer Netherlands

Buch, Englisch, Band 7, 479 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 1121 g

Reihe: Fundamental Biomedical Technologies

This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.

Zielgruppe

Research

Autoren/Hrsg.

Prokop, Ale¿

Harada, Atsushi

Iwasaki, Yasuhiko

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

Editorial and Introduction to Volume 2.- Part I Novel nanocarrier design and processing.- Proprietary nanofiber technologies and scale-up.- Magnetically responsive (nano)biocomposites.-Zwitterionic nanocarriers for gene delivery.- Stimuli-responsive polymeric nanocarriers as promising drug and gene delivery systems.-  Photo-responsive polymeric nanocarriers for on-demand drug delivery.- Part II Nanocarrier characterization and function.- Considerations on uptake and intracellular trafficking of nanocarriers.- Mucus as physiological barrier to intracellular delivery.- Investigation of nanoparticles in biological objects by electron microscopy techniques.- Gold nanoparticles for high resolution imaging in modern immunocytochemistry.- Design of functional polymers for intracellular drug nucleic acids delivery.- Membrane-domain-selective drug targeting based on lipid modification.- Multifuntional protein-based nanoparticles for theragnosis.- Cytocompatible phospholipid polymer for noninvasive nanodevice.- Intracellular protein delivery using self-assembled amphiphilic polysaccharide nanogels.- Part III Simulation for delivery and function.- Molecular dynamics simulations of polyplexes and lipoplexes.- Computational studies of highly pegylated sterically stabilized micelles self-assembly and drug solubilization.- Toward intracellular delivery and drug discovery,Stochastic logic networks as efficient computational models for gene regulatory networks.- Part IV Nanocarriers for drug discovery and treatment.- Nanodiamonds as intracellular probes for imaging in biology and medicine.- Intracellular delivery of RNA using RNA-binding proteins or peptides.- Hyaluronic acid based nanofibers for wound dressing and drug delivery carriers.- Potential of siRNA therapy in chronic myeloid leukemia.