Prokop / Iwasaki / Harada Intracellular Delivery II

Fundamentals and Applications
2014
ISBN: 978-94-017-8896-0
Verlag: Springer Netherland
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 7, 479 Seiten, eBook

Reihe: Fundamental Biomedical Technologies

This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.

Zielgruppe

Research

Autoren/Hrsg.

Prokop, Aleš

Iwasaki, Yasuhiko

Harada, Atsushi

Prokop, Ales

Inhaltsverzeichnis

Editorial and Introduction to Volume 2.-
Part I Novel nanocarrier design and processing.-
Proprietary nanofiber technologies and scale-up.- Magnetically responsive (nano)biocomposites.-Zwitterionic nanocarriers for gene delivery.- Stimuli-responsive polymeric nanocarriers as promising drug and gene delivery systems.-  Photo-responsive polymeric nanocarriers for on-demand drug delivery.-
Part II Nanocarrier characterization and function.-
Considerations on uptake and intracellular trafficking of nanocarriers.- Mucus as physiological barrier to intracellular delivery.- Investigation of nanoparticles in biological objects by electron microscopy techniques.- Gold nanoparticles for high resolution imaging in modern immunocytochemistry.- Design of functional polymers for intracellular drug nucleic acids delivery.- Membrane-domain-selective drug targeting based on lipid modification.- Multifuntional protein-based nanoparticles for theragnosis.- Cytocompatible phospholipid polymer for noninvasive nanodevice.- Intracellular protein delivery using self-assembled amphiphilic polysaccharide nanogels.-
Part III Simulation for delivery and function.-
Molecular dynamics simulations of polyplexes and lipoplexes.- Computational studies of highly pegylated sterically stabilized micelles self-assembly and drug solubilization.- Toward intracellular delivery and drug discovery,Stochastic logic networks as efficient computational models for gene regulatory networks.-
Part IV Nanocarriers for drug discovery and treatment
.- Nanodiamonds as intracellular probes for imaging in biology and medicine.- Intracellular delivery of RNA using RNA-binding proteins or peptides.- Hyaluronic acid based nanofibers for wound dressing and drug delivery carriers.- Potential of siRNA therapy in chronic myeloid leukemia.